EnragedFilia 227 Posted November 20, 2021 Popular Post Share Posted November 20, 2021 I wrote the first part of this almost exactly seven years ago for one of the contests on nyou fiction. I came up with an idea for a second part soon after, and now here it is at last, along with a full rewrite of the original. --- The girl looked down at the pamphlet for a few seconds, her expression quickly shifting from curiosity to confusion. Then she looked up and asked, "So like what does it actually do?" Clarice sighed inwardly. "Like the description there says, it's a mixture of enzymes that synthesizes a wide variety of biomolecules from commonly occurring components, so that we can research them to find any with viable medical uses." The team had tried to make the language on the volunteer information handout as simple and accessible as they could, but most of the volunteers still didn't seem to understand it and ended up asking Clarice to explain everything anyway. The one across the desk from her now had a vacant expression that seemed to say she'd and stopped listening somewhere around the word 'enzymes', and Clarice found herself wondering if the girl had even seen the inside of a biology classroom since high school. "So far we've identified several that might be useful in treating conditions including... um," the girl's vacant look was still there, her confusion slowly deepening, and she glanced down at the cup on the desk as if looking at the formula itself could tell her something. Realizing that this was getting nowhere, Clarice gave another silent sigh and continued, "well, like keeping skin clear and healthy, for one thing, and-" The volunteer's face lit up instantly. "Really? Aw great." After that Clarice just had to go over the details of the stipend and show her where to sign, and then the girl swallowed the formula and left to hang out at the coffee place across the street for the next half hour. Clarice grumbled to herself a little as she sat back down behind the campus health center reception desk. It was just like Camille said earlier. Even a girl with only the vaguest understanding of biology or medical research knew something about skin care, and all it took to get a confused undergrad volunteer to sign her consent form was a quick mention of 'clear healthy skin'. At least it wasn't lying - one of the most promising potential applications they were looking into was a treatment for certain forms of early-onset heritable hyperkeratosis - but Clarice just didn't like having to work around other people's ignorance like that. She kept grumbling silently about it for a few minutes until her next volunteer arrived. It was another undergrad girl, and from the mermaid logo on her cup it looked like this one had just been hanging out at that same coffee place. She paused by the door and lifted that cup, tilting her head back and striking an impressive pose in the light from the window as she drank. She was tall and slim and athletic, with nicely toned abs and very nicely toned legs. She had shoulder-length light brown hair with striking platinum blonde highlights, pulled back into a simple ponytail, and she was wearing a cute sleeveless crop top and cute tight denim short shorts and cute little strappy flip-flop-style sandals. Her outfit looked perfect for staying comfortable in today's summer heat, and one couldn't help but notice the way it nicely showed off her abs and her legs too. Finishing the last of her coffee, she tossed the empty cup in the trash and came up to the desk where Clarice was waiting. "Hi, I'm Tara. I saw your ad earlier, are you still looking for volunteers?" the girl asked hopefully. Clarice gave her the usual bright and cheerful welcome and handed her the information pamphlet and showed her the formula, and unlike that last airhead, when Tara opened the pamphlet and started to read it she remained eager and focused. "Okay, so it's an enzyme for synthesizing some kind of designer medical treatments," Having quickly summarized the handout's information, she looked up and asked, "Well, what kind of substrate does your enzyme act on, and what are you working on developing treatments for?" Clarice happily answered her questions, somewhat heartened at a prospective volunteer who actually seemed to understand her explanation. Even though Tara didn't seem to be a science major or anything, she at least remembered enough terminology to ask relevant questions, which was more than could be said for most of today's volunteers. Clarice ended up going into quite a bit more detail than usual, and while she was explaining everything Tara took out a big bottle of water from her cute backpack and cracked it open to take a few long sips. "Right now we're still trying to demonstrate that the whole approach will produce the quantity, and most importantly the variety that we need to make it worthwhile. According to the theory everything should be viable, but the only way to really be sure is testing with volunteers," Clarice concluded with a note of cautious optimism. "Well, it all sounds interesting anyway," Tara replied, chuckling. "And I could really use the money right now. So I just need to sign here, take this and then give a sample, right?" She looked down at the cup and the consent form and reached for the pen. "That's right," Clarice nodded, then glanced away quickly. When Tara leaned over the counter like that, one couldn't help but notice the way her low-cut crop top showed off her cleavage. "Uh, you can come back in about a half hour for that part." Tara stopped with her hand poised over the signature line and looked up. "Oh, I don't need to wait or anything. I'm all ready to go right now." "Yes, you can take the formula right away. It's just after that you'll just need to wait about a half hour for the enzyme to take effect." "Oh right, of course." Tara set the pen down, frowning. "It's just, I was kinda on the way to my final right now. Does it have to be in a half hour? How about if I come back a little later, in like an hour or two?" "That shouldn't be a problem." Most of the volunteers had wanted to get everything over with as soon as possible, but as far as Clarice knew there wasn't any reason why waiting a little longer should make a difference. "Great!" Tara exclaimed, grinning again. "I'll see you in a little while, then." She finished signing and swallowed the formula, washing it down with a few more big gulps from her water bottle, and then she left. Clarice wished her luck with her final and sat back down to wait for the next volunteer. Two and a half hours later she was still sitting there when the door opened again. Clarice got up right away with a smile on her face, which disappeared when she saw who it was. "Heyyy, how are you doing over here?" Camille asked with a smirk as she came up and leaned on the desk. "Got a lot of volunteers? Betcha I got more," she snickered. Camille was the other postdoc working on this project, and as usual she had found a way to turn it into a competition. Clarice sighed softly, annoyed. "Come on, Cam. You know perfectly well this is research, not some kind of race." "Yeah, yeah, yeah," Cam waved away her objections, "just because it's research doesn't mean we can't have a little fun with it. Anyway, I already dropped my samples off at the lab and the results should be ready soon, so just meet me there when you've got enough." She trotted off down the hall to the lab, ignoring Clarice's second annoyed sigh. Even though Clarice was pretty sure they had all the samples the project needed already, there was still something she had to wait for. So she sat back down and waited, but she didn't have to wait long. Not quite a half hour later the door opened again, and this time it was just who Clarice was hoping for. "Oh, Tara. I'm glad to see you again. I was starting to get worried that you wouldn't make it." "Uh-huh. Me too," Tara replied as she approached the desk, "I'm really glad I made it." Her voice seemed a bit strained and there was something odd about the way she was walking. "So um, I can just give you the sample right now, right?" "Of course. Come right through here," Clarice gestured to the door just next to the reception desk. "You'll just need this first..." She went over and knelt to reach into the cabinet by that door. Remembering how she would sometimes feel after a long final, she turned her head to make a sympathetic remark, but froze with a little surprised gasp when she saw and suddenly realized what was odd. Tara's face was set in intense concentration, her mouth a thin line and her cheeks gently flushed. She was walking with stiff, careful steps, her arms held at her sides and her hands balled into fists. But most striking of all was Tara's bare midriff, where one couldn't help but notice that her outfit was now showing off her nice firm abs along with a very firm, very round and very prominent bulge that could only be made by a very large and extremely full bladder. For a long moment Clarice could only stare at the broad swell of Tara's lower abdomen, extending from just above her bellybutton all the way down to disappear inside her shorts. Everything about the way Tara was walking seemed to suddenly make perfect sense, and it gave a whole new meaning to what she just said: Tara *really* had to give her sample *right* now. After a few last unsteady steps she stood right in front of the door, growing even more obviously uncomfortable by the second. Her hips were squirming and wiggling, her toes were tensed and pressed into the foam of her flip-flops, her arms were trembling, and her face was flushing brighter and brighter. She started to slowly lean forward at the waist as her feet slowly rose onto tiptoes, even as her toes themselves wiggled and squirmed. She took a shuddering breath and looked down, saying only, "Um..." "Oh!" Clarice exclaimed as she was startled back to attention and suddenly realized how long she had been staring at the extraordinary sight. She reached into the cabinet with the rows of cups, then paused for a moment and reached past them, all the way to the back. "I, um... yes, you'll just, um... take this." Standing up quickly, she unscrewed the cap from the extra-large sample cup and held it out with one hand while she yanked open the bathroom door with the other. Tara reached to take the cup, but before she could she froze and gasped, her eyes going wide. "Oh no..." she squeaked in a tiny horrified voice, and Clarice realized what that meant and looked down just as Tara thrust her hands into her crotch, trembling even more and flushing even brighter than ever. She stood motionless like that for a long moment, then snatched the sample cup from Clarice's hand and zipped past her into the bathroom. She gasped again and started to undo her shorts, her free hand trembling so badly she could only fumble at the button on her fly while she gasped again and then again, until finally it came open. In a single motion she grabbed the back of her shorts and yanked them down, and Clarice looked away just a bit too late to keep from seeing. As soon as she averted her eyes she heard the loud splattering, along with the soft hissing and the much louder moan of Tara's intense relief. "She made it," Clarice whispered, with considerable relief of her own. "I'm really glad she made it." The splattering sound steadily changed into splashing, while the moan turned into a long breathy sigh. Clarice reached back and felt for the door handle, careful to avoid looking as she closed the bathroom door. That muted the hissing but not the steady burbling splashes of a very powerful stream pouring into a sample cup at very close range, so she had to stand and listen to Tara producing her urine sample. It went on and on and on, and when the mighty noise finally faded away it was only a little while longer until the door opened. Tara was again fully dressed and held the very full cup very carefully, and Clarice took it and carefully screwed the top back on. She felt a bit more uncomfortable than usual as they went back to the desk to take care of the final signature and the stipend, but Tara didn't seem to notice as she took her receipt and left, still just a bit flushed and grinning with contentment. As soon as that was done Clarice got all the samples together and headed down to the lab where Camille was already waiting. She looked up from entering her initial data and smirked, "Looks like I got two more test subjects than you after all." Clarice just gave her the exasperated sigh that always meant 'quit trying to turn everything into a contest' while she arranged her set of samples alongside Cam's for analysis. "Still, your samples might have better results, so you haven't lost yet." Cam was still smirking. The results that mattered were what synthesis products they could identify in the samples. As long as even a few of those samples met their projections it would be enough to proceed to the next phase of research, but beyond that it didn't really matter how many they had. Clarice just gave Cam a quick glare and sat down to start entering her own data while they awaited the results of the analysis. When it was finished they both leaned over together to look at the screen, and for a few moments they stared in silence. Then Clarice breathed, "Wow..." her eyes going wide. "That's-" "How did you do that!" Cam burst out. "This is one of yours, isn't it?" She jabbed a finger at the screen, and the same set of numbers where Clarice was still staring. Most of the results on the screen were just about what they expected, right around the ranges predicted by their experimental hypothesis. But the numbers in one column, from one particular sample, were far higher, exceeding all of their projections and surpassing even their most optimistic predictions. Cam went on, "How did one of yours end up so much better than all of mine? You better not have gone messing with anything because-" "Will you forget about your stupid imaginary competition already, this is important!" Clarice cut her off hotly as she belatedly registered the accusation. Leaning closer, she pointed at the screen herself. "If we can confirm these results and produce them consistently, our little project could turn into a major avenue of research. Got it?" Cam closed her mouth, rethinking her indignant reply and turning back to the screen. The rest didn't need to be said. A breakthrough like that would mean major funding and prestige for the department, along with prestige and opportunities for the two lucky postdocs that made the discovery. But first they had to confirm the results. "Okay, so what does it mean?" Cam was calming down and focusing now. "There has to be something special about that sample, right? Unless it's just a fluke, or an error with the analyzer." "I'll stay here and analyze it some more to be sure," Clarice was looking at the ID number of the special sample and thinking about what it might mean. "But I think I might have an idea what happened..." -- Experiment #1: The Final It was getting late when Clarice finished her analysis, and she was stretching her stiff shoulders as she came out of the lab. "Hey." Camille looked up as she approached. "Have you figured it out, then?" "The results are definitely accurate, if that's what you mean." She'd put that sample through every kind of analysis the lab could do, and every time the results were consistent. "Now we'll need to try to find out what happened. Like I said, I might-" "Too late then!" Cam burst out with a big grin. "Because I've got our answer right here. Take a look," she motioned Clarice over and turned her monitor. "Huh?" Clarice came over, frowning in confusion. "What do you mean? Did somebody else already publish something after all? Because I thought we checked all the archives for..." She trailed off. It wasn't any journal archive on Camille's screen, it was a video. The scene showed a big, moderately crowded lecture hall viewed from multiple angles. It looked like the feed from all the room's security cameras side by side. One of those cameras had a view of the main door, where a few more students were coming in and taking their seats. She watched, still wondering what it was all supposed to mean, and she was about to ask when she saw a familiar face. "Oh! That's-" "It's her, isn't it? I knew it! And I knew you'd recognize her too, with the highlights in her hair." Cam sounded a little giddy just now, and Clarice glanced at the pair of empty cans on her desk with the big colorful logos. Camille always had a can of that energy drink of hers when she was doing lab work, and she usually didn't stay this late, so tonight she must have had that second can to keep going a little longer. "It's... um, yeah, it's her." Clarice recognized that crop top and those short shorts and those long toned legs just as easily as the platinum blonde streaks in the girl's hair. That was Tara on the screen, which meant this video had to be from Tara's final earlier today. "See, I was looking for her name in your notes but when I saw what time you signed her up and what time you got her sample I was like, 'why did she wait so long?' and then I remembered 'duh, it's finals week!'" Cam was starting to ramble like she sometimes did when she was running on caffeine. Clarice nodded vaguely and sat down beside her, still focused on the screen. Tara was on all the cameras at once now as she sat at her desk and set her half-full water bottle next to her test. "So I was looking through today's final schedules and I thought I'd check the security cameras but as soon as I went to the server I found this instead." Another camera angle appeared then, a zoomed-in view from the back of the room. It was focused on the back of Tara's desk, so when Tara sat down it had a perfect view of the back of Tara's shorts. "Um..." Clarice muttered, suddenly becoming uncomfortable, "Is that, uh..." "Yeah, see, I found it on the department server." Cam snickered. "I guess someone noticed something interesting that happened at this test and put this together from the security camera footage. Oh but don't worry, I pulled all the original footage too just in case." All security camera footage from exam periods was freely available for anyone with an account to access as part of a 'transparency and honesty' initiative. That didn't answer her actual question, however. "Right but, uh..." Clarice pointed at the screen this time, "Is it trying to look at her..." "Yeah, see apparently there's some kind of rumor that what's-her-name there never wears underwear, and I guess someone was trying to find out if it's true." Cam snickered some more. "That's why the camera keeps zooming in on her butt, to see if it'll catch a glimpse of her buttcrack." "Her name's Tara..." Clarice muttered with a little grimace. She would have been more comfortable with the term 'gluteal cleavage', particularly just now that she found herself thinking about what happened earlier at the health center and especially what happened in the health center bathroom. After a moment Tara leaned over the papers on her desk, and another camera angle appeared. This one was a zoomed-in view from the camera at the front of the room, behind the podium and above the darkened smart board there, and when Tara leaned over she gave that camera a perfect view right down her very low-cut crop top. Zoomed in like this, it was just about clear enough to make it just about impossible not to notice that Tara was definitely not wearing a bra. Clarice looked away, uncomfortable again, and Cam pointed out, "Don't worry, it skips most of this boring part." Clarice glanced at the timestamp there in the corner, and sure enough after just a few seconds it flickered as the video skipped ahead several minutes. Tara was still sitting focused on her test, and hardly even looked up as she reached over for her water bottle. The camera behind her responded by zooming even closer to focus on the way her stretch made her shorts stretch and squeeze her rear end in new and interesting ways. As she raised the bottle to her lips the camera in front of her zoomed closer too, focused on the way her top strained and stretched over her firm and very perky breasts. Then she put the bottle back down and there was another skip, right to another sip that was just a little longer and another set of zooms just a little closer. After the third skip Tara took a longer drink, and this time Clarice noticed her legs were crossed. With the next skip she noticed Tara's leg bouncing slightly, the flip-flop dangling carelessly from her foot, and by the next it had fallen off and lay upside-down on the floor. Before long both her legs were bouncing rhythmically, and then she was gently rocking back and forth and her hips were beginning to wiggle. With every skip she seemed to be squirming more and more, but she just kept drinking from her nearly empty water bottle, too focused on her test to notice what was happening. But Clarice noticed, and she knew just what it was and exactly what it meant, and she found herself thinking back to what she saw at the health center earlier, and she also found herself thinking about biology. Because earlier she saw Tara arrive at the health center just finishing a nice big coffee drink, and then she saw Tara leave the health center just starting a nice big bottle of water, and just now she saw Tara arriving at her final with that bottle of water already half-empty. So now she could picture what was happening inside Tara's body just perfectly, all that fluid passing through her digestive system and into her bloodstream, the sharp drop in tonicity inhibiting vasopressin release and deactivating aquaporin in her nephrons and reducing their reabsorbtion rate, letting the excess hydration flow straight through her kidneys to her ureters for peristalsis to pump right into her bladder. And her bladder slowly and steadily filling up and swelling, until it swelled enough to trigger the detrusor stretch receptors to send their signals back up to the rostral pons. There the Barrington's Nucleus would respond and send its signals right back down to the internal sphincter and the detrusor muscle, and when Tara felt that distinctively and distinctly uncomfortable sensation it would finally notify her of was going on in her own uncomfortably full bladder. Of course, knowing all about the biology of the situation didn't really tell Clarice anything new about it. Just from the way Tara looked on the video during her final, it was becoming obvious enough that she had to go to the bathroom. And Clarice had already seen the way Tara looked at the health center after her final, right before she finally made it to the bathroom. But thinking about that now reminded Clarice of something else, of what Tara said at the health center before her final: "I'm all ready to go right now." Tara was already ready to go, she was already ready to give her sample, and she could already tell. That meant she was already feeling the discomfort that arose when her pontine micturation center sent her that signal, which meant it was already getting the signal from her stretch receptors that were already being stretched by her swelling bladder. And when she said it she had just finished drinking her coffee and just started drinking her water. After drinking all that, by the time she got to her final and sat down, Tara's system must have been quite fully hydrated already, and she was still drinking even more. And while she sat, all the excess hydration from everything she'd been drinking already along with all the additional hydration from everything she was still drinking must have been flowing freely right through her kidneys and pumping through her ureters and absolutely pouring right into her already noticeably full bladder. And that's what they were watching on the video. Tara's bladder was filling up more and more, swelling and stretching. Her stretch receptors were sending stronger and stronger signals, and the signals coming back were instructing her involuntary internal sphincter to relax at the same time as her equally involuntary detrusor muscle contracted, in order to cause her bladder to involuntarily empty itself. Needless to say, nothing like that was going to happen to Tara, thanks to her voluntary external sphincter and its well-developed reflex to contract and hold her urethra safely closed and keep the contents of her bladder safely inside. So Tara herself could simply sit and stay focused on her test while the tension between her detrusor and her subconsciously actuated sphincter grew stronger and stronger and the visible signs of her discomfort slowly but steadily grew a little more obvious. She squirmed, she shifted restlessly, she rocked slowly back and forth and her crossed legs began gently bouncing, a whole set of subconscious movements that together had the effect of applying a little extra pressure upon the vicinity of her urethra to help out her squeezing sphincter. And once the discomfort grew strong enough, it finally broke through Tara's focus into her conscious awareness. After a particularly long and intense squeeze and a little shiver that made her whole body tense up for a moment Tara looked up with an anxious and slightly worried expression. Clarice had to sympathize, especially when she thought about how much longer Tara was going to have to endure her discomfort before she hurried into the health center. For now, Tara slipped the mostly-empty water bottle back into her backpack and carefully crossed her legs, making a fully conscious effort to help with the squeezing of her sphincter muscle and hopefully help alleviate her intense discomfort. But that discomfort was still getting worse. Soon she was squirming and rocking in her seat constantly, completely unable to keep still. Her legs were bouncing more vigorously, both her flip-flops on the ground now and both her bare feet wrapped around the leg of the chair. She was biting her lip in anxiety and concentration as she struggled to focus on both her squeezing and her test. And throughout it all Tara's expression was like a silent squeal of distress that grew steadily in intensity and eloquence from "I gotta go!" into "Oh I really gotta go!" then through "Oh man, I gotta go so bad..." to "Oh no, I really gotta go right away!" before finally reaching its urgent anguished pinnacle of "I absolutely gotta go *right* now!!" Clarice could only watch in helpless horrified sympathy as that last flash of wide-eyed agony was followed by another shiver and a little gasp and a horrified wide-eyed stare that could only mean "What if I can't hold it!?" Clarice almost gasped herself when she saw it, and she had to remind herself that Tara could definitely hold it, that she already knew Tara could hold it through her whole final, because she already saw Tara when she arrived at the health center, still holding it, after her final. She already watched Tara, still holding it, hurry into the bathroom, where she could pull down her shorts and finally stop holding it and let go safely into a sample cup. But at the same moment she remembered that, she watched Tara on the screen drop her pencil and reach down with both hands and start to unbutton her fly. All her reassurances vanishing at the sight, Clarice was struck by the sudden horrifying thought that she was about to see Tara reach for the bottle in her backpack and resort to an extremely drastic emergency measure that she was sure to regret as soon as she realized she was on camera. But after just a second Tara took up her pencil and returned to her test, with her backpack still closed and her legs still crossed and her shorts still on. She was still very uncomfortable and still squirming very badly, but somehow she didn't seem quite as frantic as before. Clarice wondered why until the camera zoomed all the way in to once again focus on the back of Tara's shorts. Camille snickered and spoke up at that, "Looks like somebody got their answer after all," her snickers turned to chuckles, "and an even better view than they expected." Clarice ignored her laughing and just stared. A small but quite visible bit of Tara's gluteal cleavage was peeking out just a little from the back of Tara's shorts, and as she continued squirming the back of her shorts slipped a little lower and let it peek out a little more. After just a few seconds it was visible enough to make the truth of the rumor just about as obvious to anybody watching as it was to Clarice at the health center earlier, when she couldn't quite look away fast enough at the moment that Tara suddenly pulled down her shorts in the health center bathroom and couldn't help but see that Tara was definitely not wearing any underwear. She felt a brief pang of sympathy for Tara's slight accidental exposure, but then she remembered something else she saw at the health center and realized the other significance of Tara's descending shorts. Because if loosening her shorts like that let the back of the waistband slip down and expose her gluteal cleavage to the camera behind her, it also released the squeezing that the front of the waistband placed upon her bulging bladder, and that must be why Tara didn't look quite so uncomfortable anymore. She had never really thought much about something like that before or about just how much it might help in a situation like this, but it made sense right away and as soon as she started thinking about it she found herself thinking about how it might work, and she found herself thinking about anatomy. About Tara's bladder filling up and swelling and stretching enough to trigger her stretch receptors, and then swelling even more until it began to impinge on other nearby organs. The pelvic cavity, already quite cramped to begin with, becoming more and more crowded as the steady flow forced her bladder to steadily expand until it was completely squished and pressing right up against the anterior abdominal wall. With no more room left but her bladder still growing, the abdominal wall itself would start stretching and Tara's abdomen would start swelling, slowly and steadily developing into a big prominent bulge just like the one she saw at the health center earlier, right beneath Tara's bellybutton. But that was only when Tara came back to the health center after her final. When Tara was at the health center the first time, before her final, the waistband of her shorts was there under her bellybutton, right where that bulge would be forming. So while Tara was sitting and trying to focus on her final, with her bladder filling and beginning to stretch and her abdomen bulging and beginning to swell, it would have quickly met the resistance of her very tight shorts. With that additional constriction on top of the periodic involuntary contractions of her own detrusor muscle, the combined squeezing on poor Tara's poor bladder must have been almost unbearable. So by unbuttoning her shorts and releasing the constriction from her waistband, it made perfect sense that Tara would immediately make herself that much less uncomfortable. With her abdomen free to swell and bulge to accommodate her steadily filling and swelling bladder, Tara would have a little while longer to focus on her test. But even so, Clarice found herself wondering if that was all there was to it, and she found herself thinking about psychology. She had always suspected that any physiological effect which produced uncharacteristically pronounced results with unexpected immediacy might have a psychological component involved as well. For instance, if Tara had experienced something like this before then she might have ended up conditioning herself and induced a sort of Pavlovian response. Or if she had heard about something like this before trying it herself then she might have ended up anticipating the results and induced a sort of placebo effect. It was just the sort of fascinating question that someone might design an experiment to answer, perhaps with a sort of belt that could be remotely loosened and tightened... When she found herself thinking that, however, Clarice decided she was thinking entirely too hard about the matter, and anyway she was right in the middle of an experiment already. So she returned her focus to Tara, who was already growing very uncomfortable once again. Whatever the exact cause of her reprieve, it was turning out to be very brief. After all, whatever she might do to alleviate the tightness that was making her discomfort worse, she had absolutely no way to relieve the intense discomfort itself, or to stop her own body from making it steadily worse. With Tara's system still overhydrated her kidneys were still flowing as freely as ever, her ureters were still pumping dutifully and still filling up her already overfilled bladder even more. Tara was squirming and wiggling constantly now, rocking back and forth with her legs twisted tightly. From time to time she would freeze and stiffen with all her weight perched on a corner of the chair, her pencil held still and her whole body held tense, motionless and trembling while she clamped her legs together as hard as she could. Every time Clarice just couldn't help but picture what was happening: Tara's detrusor muscle tightening, squeezing her bladder even harder than ever, while Tara forced her sphincter muscle to squeeze just as hard to resist it. After a particularly long and particularly intense wave of squeezing that made Clarice wonder if Tara was going to have to reach for her backpack and resort to drastic measures after all, Tara suddenly put down her pencil and quickly flipped through her test, then started putting everything away. With no small relief Clarice glanced down at the timestamp to confirm that Tara's final and her extremely uncomfortable ordeal were both nearly over. Tara picked up her backpack and smiled as she hopped eagerly to her feet, only to let out a startled squeak and sit right back down. That sudden movement and the little jolt it delivered to Tara's highly overstretched bladder must have triggered another merciless squeeze from Tara's detrusor at the same time as Tara was momentarily distracted. She sat perched on the chair with her hands in her lap and her legs crossed tightly, squeezing and blushing as she tried to ignore the curious stares from the nearby students that glanced over at the sound. Clarice thought she must at least be glad that most of them had already left, not that it would matter much if she ever found out that it was all on camera anyway. When the wave passed Tara felt around with her feet to slip her flip-flops back on, then put on her backpack and stood up again, more gingerly this time. With small careful steps she started toward the front of the room, just as a smiling blonde girl in the front row stood up too and got in front of her. The blonde paused in the act of turning in her test to chat for a bit with the TA, giggling cheerfully and never even noticing Tara, who had to stand behind her waiting and squirming. Just about everyone else seemed to notice, however, especially when another very intense wave struck and Tara gasped sharply and moaned softly and bent forward, rising to her tiptoes and trembling and squirming even more than ever. Just watching her, Clarice could perfectly picture Tara's detrusor muscle contracting cruelly upon her dangerously full bladder, while Tara forced her sphincter muscle to clench just as hard as it could to keep her urethra safely closed and keep the contents of her bladder safely inside. For a long moment she stood there trembling just like that, while everyone behind her looked up one by one at the remarkable sight of a tall athletic college student acting just like a little girl who was just about to wet her little panties. Only the blonde girl never noticed, and for a moment Tara didn't notice either when that girl turned with a final giggle and trotted cheerfully out the door. Then the wave slowly receded and Tara gradually became aware of the TA sitting there staring at her. She straightened and silently handed over her test, then turned and carefully headed for the door herself, showing the camera beside it a perfect profile of her bare midriff as she passed. The still frame of that moment remained on screen beside the other cameras as the door closed behind her, and the big firm bulge clearly visible beneath Tara's bellybutton looked exactly like Clarice remembered. When it was over she sat back, emotionally exhausted from watching and sympathizing with Tara's struggle and with a whole new appreciation for the real value of her sample. She already knew what it could mean for the project, but seeing what Tara really went through to bring it safely back to them somehow made it seem even more precious. "That's it, right?" Cam sounded excited. "It's exactly what we needed!" Clarice nodded distantly. "Yeah, she gave us just what we- huh?" she started before she thought about what Cam meant. Cam went on, "This explains everything. The numbers we saw, and what happened with the sample." She giggled, still giddy and now triumphant besides. "It was in her bladder the whole time!" "It was... what?" Of course the sample was in Tara's bladder, that's why Tara had to sit through her final squirming and suffering, so that she could get back to the health center afterward to give her sample. But that wouldn't explain the numbers and the results from the sample. Unless... "The formula, I mean. The enzyme. It spent that whole time in Tira's bladder, that's how it happened!" "I told you, her name's Tara. And what does that have to do with it? Do you mean-" "It's the hormones and the pH balance, just like we were dealing with in the first place, remember?" In the earlier stages of the project they'd had to spend a bit of time and quite a bit of effort coming up with an enzyme that would remain fully active under the conditions of their experiment, including pH level and especially hormone levels. Even after all that, they'd had to exclude quite a lot of potential volunteers, in particular all males and anyone over about 26. "That whole time we were just trying for something that would keep working when a volunteer takes it, and we ended up with something that works even better in a volunteer's bladder!" "In the... oh. So then that means..." She had to admit the idea almost made sense. The enzymes would pass through the kidneys unaltered, along with all of the products and most of the major reactants. And the bladder would have a very different pH level, which had to have a major effect on their activity. They would need to do some calculations and maybe another experiment to figure out just what effect, of course. But still, it seemed like there was something else too... "So it's simple. Your girl Tara waited longer than the others, so the enzyme spent more time in the bladder and ended up being that much more effective." Clarice nodded slowly, something still tickling at the edge of her mind. Cam went on. "Now, according to the timestamps, she must have come back after about two and a half hours, right?" "Yeah, I guess. Maybe it was closer to three," she answered distantly. "The exact times should be in the system if you need to check." "Perfect! I've waited at least three hours." At that apparent nonsequitur Clarice looked up, just in time to see Cam slide halfway off her chair and lift her top slightly, just far enough to expose her midriff and reveal the quite sizable bulge there. "...Huh? Wh-what do you-" Clarice gaped and sputtered as Camille reached into her desk drawer and took out a sample cup. "Y-you mean- Are you going to-?" "I took the formula earlier, and I had plenty to drink since then," nodding vaguely toward the empty cans on the desk, Cam unscrewed the sample cup and started to undo her pants. "So my results should be just like Tara's, right?" "That's-" Camille began, trailing off as something occurred to her. "But that's self-experimentation." There were strict department policies against using any results obtained by self-experimentation, mostly designed to avoid giving researchers a reason to consider using themselves when they couldn't find volunteers for potentially dangerous experiments. "You know we can't include anything from-" "Then I won't include it," Cam said with a shrug, squatting carefully. "Anyway, this isn't even an experiment, I'll just verify our interpretation of Tara's results." She pulled her pants down to her ankles before pulling her panties down to her knees, so Clarice was able to look away in time. She shifted slightly and gingerly looked back, careful to avoid seeing something impolite. Instead she watched as Cam positioned the sample cup between her legs and gave a little sigh. There was a moment of silent suspense and then the stream shot out, with a hissing and splattering sound that gradually turned into splashing as Cam emptied her bladder and filled her cup. Clarice found herself thinking back to that other splashing stream she heard earlier. It was the same, but... it was different too. And that meant... "I got it!" she exclaimed, jumping to her feet with a gasp. Cam glanced up with a smirk, "I knew you'd figure it out. It's still a pretty nice breakthrough, but really not enough for a major-" "Not that! It's-" she struggled for words. The burst of insight was like a camera flash or a lightning bolt, illuminating every detail all at once, not like figuring things out but just seeing it laid out right there from end to end. She had to take a moment to organize the idea before she could even begin to explain any of it. "It was- the enzyme, it was in her bladder, just like you said. But it wasn't just there for longer, it-." She paused, took a breath and tried to focus and rearrange her thoughts into something more coherent. "Tara didn't just wait longer than the others. She waited as long as she *possibly* could." Cam just frowned and nodded slightly. "So that whole time the enzyme was working, right? But while it was working she was still waiting and- I mean, she was still holding it, so the conditions were shifting. I mean, the- the pH level and-" "And the hormones," Cam breathed, her voice rising and quavering as the same realization dawned on her too. "The hormone levels were shifting while the enzyme was still working. And the reaction's products-" "The parasympathetic response triggers the Pontin- th- the PMR," Clarice took another breath and forced herself to slow down a little. "So that once the reaction gets going the stress hormones spike, and that shifts the conditions for the enzyme. But now since the reaction's products are there too-" "They become the new reactants... in a second-order reaction!" Cam exclaimed breathlessly as the last piece of the puzzle slipped into place. "That's where the extra products came from, there was a whole new set of reactions that we never even considered." "And it could keep going too. There's no telling how many iterations are possible with different permutations of... well, hormone levels, and, uh-" "That girl... she gave us a new set of reactions with a whole new set of products," Cam went on, "and all she did was keep holding it a little more." "There was nothing little about it," Clarice muttered with some irritation. "I mean you saw what happened too." She shuddered slightly at the thought of what poor Tara had to go through. Camille looked down and shifted her legs slightly to examine the bulge beneath her bellybutton. Again Clarice jerked her eyes away from the impolite view. She didn't need to look any longer than that to tell that as big and impressive as it might be, Cam's bulge was nothing at all like Tara's, and her stream was nothing at all like Tara's either. That stream was just starting to taper off now as her bladder finished emptying itself, but in just the time it took to fill her sample cup everything had changed. "You're right," Cam admitted, "this really is a major breakthrough." She looked up and started to grin. "And now we've really got to keep researching it." Clarice nodded. "Of course. We'll need to come up with a whole new experiment." She frowned in concentration as she thought about how to design one. There were so many new factors that might be relevant to their new hypothesis, so many things they hadn't even considered before. "You've been in the lab for a few hours, right?" Camille asked casually as she screwed the lid back on her sample cup. "Mm-hmm, I guess." Lost in thought, Clarice answered before she thought to wonder about the meaning of the question. "And you were at the reception desk for a few hours before that, weren't you?" Cam was pulling her pants back up. "I-" Clarice looked over and narrowed her eyes suspiciously. "Well yeah, since just after lunch. Why does that-" "Great!" Cam declared, setting her sample cup down on the desk with a thump, then reaching again into her desk drawer. "And I noticed you had that energy drink earlier, too." Clarice nodded uneasily. "Um, yeah. I had three today..." she trailed off as the direction of Cam's questions and their meaning began to dawn on her. "Wait, do you mean-" "Oh, that's perfect," Cam declared as she got out a fresh dose of the formula they'd prepared for today's volunteers. Looking at that, Clarice found herself suddenly becoming highly aware of a gentle yet quite distinct and quite uncomfortable feeling. A feeling that must have been gradually building while she sat in the lab, too focused on her work to notice it at all. A feeling that, she now suspected, was going to get quite a bit more uncomfortable before her work was quite finished tonight. "So I guess you shouldn't need too much longer then," Cam concluded, rising from the drawer and plunking the formula down on the desk, along with a fresh empty sample cup. Her suspicions confirmed, Clarice's face fell, while Cam just grinned happily and added, "Tara showed us just how long she could hold it, so now let's just see how long you can hold it." -- Experiment #2: The Game Another cheer went up and she swept her view over the audience again, paying particular attention to the group of girls in the front row. "Wow, this is getting really good," Cam said next to her. "How does it look over there?" Clarice gave a little irritated sigh before she replied, "It's coming along alright." After another sweep of the front row she lowered her binoculars and glanced over. Just as she thought, Camille seemed to be paying a lot more attention to what was happening with the game down on the field as with the audience up in the stands. They needed binoculars to see much of anything from these seats all the way up in the highest row, which at least meant they could watch the audience without being too obvious about it. Raising her own binoculars again, she looked back at the front row. The last of the cheers were fading now and the girls that had stood up were sitting back down, while the girls that had only leaned forward to cheer leaned back again, and just about all of them crossed their legs. When the last of the excitement faded it seemed to be replaced by a sense of anxious restlessness, and when a girl all the way at the far end of the front row leaned over to say something to the girl next to her Clarice couldn't help but imagine that she was saying something like, 'I gotta go'. "Everything's progressing just as expected." Clarice went on without lowering her binoculars again. Down there a different girl from the second row got to her feet and started moving away, only to stop with a look of dismay when she saw the big long line right where she was headed. She hesitated, looking nervously back down to the field, then returned to her seat, still holding it. "It's starting to look like this might just work out after all" "Well of course!" Cam said with a snicker, not quite bragging but still sounding a bit smug. "I knew you'd change your mind." It was Camille that came up with this whole idea, and at first Clarice had her doubts about it. There were just so many unpredictable factors, and Cam was never exactly the best at planning out all the details and thinking through every little possibility in her experimental designs. But at least so far everything seemed to be turning out exactly like she said it would. It was most visible there in the first few rows, but wherever Clarice looked she saw the same thing. All over the crowded stadium there were girls looking restless and crossing their legs and even starting to squirm, showing all the signs that they all had to go. And it was all thanks to Cam's plan, and everything that she and Clarice set up earlier, before the game started. First they'd checked on the 'collection apparatus'. It had been set up in the parking lot last night, so all they really had to do was make sure that none of the equipment got damaged in transport or anything. The first few sports fans were starting to arrive then, just waiting there in the parking lot chatting and drinking. Cam said that was a sort of tradition before all the bigger games, and sometimes a few of the smaller but more important games like this one. After a while they started lining up at the ticket counters, and it was time for Cam to get to work. 'Hi there! We're here from the health center for a little experiment,' she could still hear that opening line, the one they'd practiced so many times to get just enough of a 'bright and breezy' tone to soften the 'sales pitch'. 'Would you like to help out with a quick taste test?' She could still see the prospective volunteers' faces too, the uncomfortable wariness there disappearing when it became apparent they weren't being asked to donate anything or fill out any opinion survey. And then the eagerness that appeared when a volunteer saw what was in their little cooler. It was a very warm morning, after all, and anyone that didn't bring anything to drink before the game must have been regretting it, while anyone that did had just had to leave it behind in the parking lot. So the offer of a nice cold drink must have been a very welcome one to a volunteer who was already stuck in line anyway, and even better if she could help out 'the health center' all without doing anything more difficult than presenting a student ID and answering a few questions about the taste. The answers they got were mostly along the lines of 'tart and tangy', which made sense since it was mostly just ordinary fruit juice, but of course the taste test wasn't the real point. Because when those volunteers signed the questionnaires they also signed a consent form, and hardly any of them even glanced through it when they did. And nobody at all seemed to notice the part on the third page where it mentioned 'collecting samples'. So they'd ended up with plenty of volunteers who happily drank their juice with the formula in it and signed their forms with the consent release, and now all that was left to do was wait until it was time to collect all their samples. Of course there were plenty of guys that ended up volunteering too, but Cam had planned for that and made sure to bring plenty of extra juice without any formula, both for guys and for any girls that wanted a refill. They couldn't give any of their test subjects a double dose of formula, after all, so any girls that were extra thirsty just got extra fruit juice, and that ought to be just fine for their experiment. "Hey, it really is coming along over there," Cam said, and swept her view over the audience. There seemed to be some kind of lull in the action on the field, and Cam seemed to have remembered that they were supposed to be here monitoring their experiment and not just watching a game. Quite a few audience members seemed to have noticed the lull as well, and were taking advantage of the opportunity to get up and take a quick break. Clarice watched as a little group of girls from somewhere around the third row got up together and hurried over to the back of the nearest line and waited there, looking a little nervous and quite a bit restless. They waited just about long enough for the line to start to move a little before there was another cheer as the action seemed to resume, and those girls looked anxiously back down at the field and almost all of them hurried right back to their seats, still holding it. "Oh yeah, looks like this is going to work out just great," Cam chuckled, turning her attention back to the game too. Apparently it was a really exiting game, just like Camille said it would be. Clarice herself could hardly even make sense of what was going on when she looked at the field, let alone everything Cam had excitedly explained about it earlier. From what she could understand it had to do with some longstanding intercollegiate rivalry and both teams' star players returning from some sort of hiatus, but whatever Camille said the reason for it was, Clarice could easily see the truth of it right in front of her. Just about the whole crowd seemed to be really getting into it and growing steadily more excited, especially there in the first few rows. And at the same time, Clarice could see just as easily that quite a lot of the crowd was also growing steadily more uncomfortable, especially right there in the front row. But even as the girls there became more and more nervous and restless, their tightly crossed legs starting to bounce irrhythmically, not a single one got up from her seat. They all just sat there and they all just kept holding it, just like Cam said they would. 'Those are the biggest fans, there in the front row,' she'd explained earlier, while they watched those girls in colorful miniskirts take their seats, 'so they're gonna be our best shot at getting results.' Clarice had nodded along. She recognized most of the girls there from the parking lot when they'd been drinking before the game, and almost all of them from the ticket line when they'd participated in the 'taste test', so she could easily picture just what was happening inside those girls' bodies. Even as they all sat down, all ready to enjoy the game, their kidneys would be all ready to send all the excess hydration from all they had to drink right through their ureters and right into their bladders. Then the formula could do its work, and before long they would all have their samples all ready. That just left the question of how many of those girls would actually end up delivering those samples to the collection apparatus in the parking lot. Cam had laughed off that concern, however, saying, 'Don't worry. Like I just said, they're the biggest fans.' Then she'd explained that too. 'See, the stadium has nowhere near enough bathrooms. I guess the designers decided to like almost double the seating capacity at the last minute or something, but they couldn't double everything else when they did, so now there's always a big line at almost every game.' Clarice had nodded again, starting to understand. Of course if the stadium had a little too much seating capacity and not quite enough bathroom capacity it would end up having a really big line at all the bathrooms, especially when it was filled almost to capacity like this one was right now. 'Anyway, the fans that are at all the games know all about the lines, so they know there's no way to go for a bathroom break without missing at least a few plays.' Of course having to wait in a line like that during the game would mean missing something, and of course a sports fan wouldn't want to have to miss anything, especially any of a game that was as exciting as this one seemed to be. So if those girls in the front row were the biggest sports fans, then of course every one of them wouldn't want to get up to take a bathroom break if she could possibly help it. 'The way this game is going, those girls definitely won't want to miss a single play,' Cam had concluded with a self-satisfied smirk, 'so they'll definitely want to keep holding it.' That was the real purpose of Cam's experimental design, and the real reason they were here at the stadium. They could provide every volunteer with the formula along with plenty of juice to send it into her bladder where it could get to work, but it was the game itself that provided that volunteer with the motivation to keep it there in her uncomfortably full bladder and resist the resulting discomfort while it did its work. So now, just like Tara when she ended up stuck in the middle of her final with her bladder rapidly filling up and she just had to keep holding it and holding it, every one of those girls there in the front row was going to end up stuck in the middle of the very exciting game right when her bladder was filling right up, and she was just going to have to keep holding it and holding it and holding it. Clarice just had to sympathize with them after watching everything that Tara went through, and especially after going through the same thing herself. After their breakthrough in the lab and once they'd analyzed Cam's 'verification' sample, the two of them had gone back to the lounge to discuss everything, and to wait until Clarice was ready to produce her own 'verification' sample. Mostly they were brainstorming the next experiment to test their theories, and for a while that was enough to keep her comfortably distracted. Except apparently brainstorming wasn't quite as distracting as lab work, and she already had to go pretty bad and it just kept getting worse and worse until before long she had to go really bad and she could hardly concentrate on brainstorming at all. Again and again she found herself picturing what was going on inside her, all the excess hydration from all those energy drinks she had earlier flowing right through her kidneys into her bladder, and her bladder stretching and swelling as it filled up, triggering the stretch receptors that were making her more and more uncomfortable. For a while Cam kept on brainstorming and coming up with her experimental design all by herself, well after Clarice was hardly even listening anymore, until at last she fell silent too and only watched as Clarice squirmed and struggled as hard as she could to just keep holding it. The more she thought about it the more she found herself sympathizing with all the volunteers that were going through the same thing right now, more and more of them starting to squirm, rocking forward and back in their seats, their tightly crossed legs bouncing more and more restlessly even as she watched. When that girl at the far end of the front row leaned over again and said something to the girl next to her, this time Clarice could only imagine that she was saying 'I really gotta go'. She was starting to suspect that particular girl might not be quite motivated enough deliver her sample to the parking lot after all, no matter how big a sports fan she might be. It was only going to keep getting worse, after all, and there would be a convenient break pretty soon, halfway through the game. Clarice had to expect that girl and probably quite a few of the others in the front rows there might just decide to take their chances and hope they could get through the line and use the bathroom and get back without missing too much of the game. She kept waiting and kept watching, and sure enough it just kept getting worse all over the stadium and especially there in the first few rows. By the time the teams started to leave the field it seemed like almost every girl there was squirming at least a little. Clarice fully expected to see quite a few of those girls get up and hurry to join the lines at the bathrooms, maybe even most of them. But to her surprise and confusion not a single one did. She was leaning over toward Cam to say something about it when she was interrupted by a fresh wave of cheering. It was the cheerleaders, filing out of the locker room and lining up right near the middle of the field, along with some new music. "The squad always puts on a pretty good halftime show," Cam was saying. "And I think they might have something special planned for today." Of course. This was the halftime show that the cheerleaders were about to perform. Because the break was called halftime, now she remembered. "I hope so anyway. If it's good enough they could even help us out a little." Clarice nodded, starting to understand. It looked like most of the audience was willing to miss the halftime show in exchange for the chance to take a badly needed bathroom break, even those who'd been putting it off until now. But the 'biggest sports fans' there in the first few rows all seemed to be fans of the halftime show too. Only a few from the third and maybe the second rows were getting up, and none at all from the first. They all just sat there and kept squirming and kept holding it, watching the cheerleaders and their show just as intently as they watched the game, even though Clarice could tell almost all of them had to be really uncomfortable by now. And when the cheerleaders' show got to its big finale the girls there scooted forward like they were about to jump up as soon as it was over, and Clarice had to imagine they were all getting ready to dash for the bathrooms in the hopes of getting there and back in time for the second half of the game. Sure enough, as soon as the cheerleaders were finished and the crowd started to cheer the entire front row leaped up all at once, except instead of hurrying away the girls all jumped on top of their seats and raised their pom-poms over their heads and gave a cheer of their own. They were dancing, Clarice realized after a moment of confusion. Standing on their chairs like that they could only sort of hop in place and twist around and shake those pom-poms they'd pulled out from under their seats, but still they were putting on a show just like the cheerleaders just did. "Oh wow," Cam said with a laugh, "I guess this is what I heard about. It wasn't the cheerleaders, it was those fans that had something special planned." Clarice nodded, understanding right away. It explained why they were all wearing miniskirts, for one thing, and it explained why there were only girls there in the front row. Those girls must have planned everything out in advance, especially to have brought those pom-poms in and stashed them under their seats, and even their outfits must have been selected specifically to resemble the cheerleaders' costumes, she could see now. Their tiny little colorful miniskirts looked just like the cheerleaders' except a little lighter and shorter, and their tight colorful tops looked like the cheerleaders' except a bit tighter and more low-cut. And when a few of the girls started doing high kicks she could see that even their very colorful underwear looked a little like the cheerleaders' costumes' underwear too, except a lot tinier and skimpier. Apparently the audience noticed that too, and they seemed to really appreciate the sight because they were cheering even more than before. That encouraged the girls to keep kicking even more and even higher, until just about every one was flashing her skimpy little panties. "They sure don't mind giving the crowd what they want," Cam was still laughing as the cheers went up, and she grinned with satisfaction as the show wound down and the cheers faded. "And I think they just gave us what we want, too." Clarice winced in sympathy as she looked again and understood. Those girls in the front row were sitting back down, and she noticed one petite girl with a cute but sort of mousy look sitting right near the end glance over her shoulder, only to turn back around with a very nervous expression when she saw what the lines looked like now. Those lines were longer than ever, and with the halftime break almost over there was simply no way that girl or anyone else could get in line now without missing most of the rest of the game. "She missed her chance," Clarice muttered. That petite girl definitely had to go pretty bad, and the halftime break was the best chance she was going to get, but she just missed it. "They all missed their chance." Just about all the other girls in the front row there had to go just about that bad too, since they'd all been holding it the entire first half of the game. And now that they'd all just missed the chance to go at the halftime break, they were all going to have to just keep holding it. "I know. It's even better than I expected," Cam looked up, still grinning. "I was just hoping we wouldn't lose them all at halftime, but thanks to that halftime show of theirs we didn't lose any." Clarice nodded along, with a slight grimace at how Cam had put it. "Since those are the biggest fans they're at every game so they know all about the stadium's bathroom situation," she went on. "So every one of them knows better than to try to wait in line, except maybe at halftime if she really has to go." She giggled again. "And I guess when they planned their little bonus halftime show for today, they just weren't planning that anyone would have to go that bad." With a fresh grin she concluded, "They all planned to just hold it until the end of the game, and now they have to go really bad but they just have to hold it anyway." Watching it now, Clarice had to admit that it looked like Cam was right, and she had to shudder with sympathy too. None of the girls in the front row made any move to get up, and only a couple of them even glanced back at the lines, even as the evidence of their discomfort returned just like before and just kept getting worse. She looked down and focused on one and then another, and from every girl she saw some kind of sign. That girl there, bouncing in her seat with restless energy. That girl a few seats down, perched on it stiffly and keeping very still. Both of the girls beside her were rocking steadily back and forth, and all the way at the end one girl was outright squirming. After a second that girl turned to her friend, and Clarice could practically hear her saying 'I gotta go so bad.' She couldn't help but sympathize with what they were all going through, and she couldn't help but think back and remember what it was like when she went through it herself. Sitting in the break room and squirming as she tried to listen to Cam going on about her experimental design. And then just sitting and squirming and squeezing as she struggled to keep holding it and holding it. Really she didn't even need to keep holding it anywhere near as long as she did just for verification, but every time she thought about just popping the cap off her sample cup and just letting go already she found herself thinking about Tara, and she just couldn't do it. Because poor Tara never had that option, she never had a sample cup with her so she never even had a choice. She was stuck there taking her final and the whole time she just had to keep holding it, and then after that she had to keep holding it the whole way back to the health center. She ended up holding it just about as long as she possibly could, until her poor bladder was so incredibly full that it must have been almost unbearable, just to safely deliver her precious sample. And she never even knew anything about how precious that sample really was. They only discovered that afterward, and they owed the breakthrough to Tara and everything she went through. Thinking about it that way, it felt like Clarice owed it to Tara to go through the same thing herself and hold it as long as she could. That was the motivation she needed the other day when she sat there in the break room squirming and squeezing, and it seemed like today the game itself was the motivation the sports fans needed while they sat there struggling and squirming in the front row. Almost all of the first three rows were clearly squirming now, or at least beginning to, and almost all the rest were clearly trying very hard not to, sitting very stiffly and keeping very still in contrast to the restlessness all around. "Wow, this is going so great. I can hardly believe it," Camille muttered without looking away. "And the game is getting so exciting, nobody's gonna want to miss any of it." Clarice nodded agreement. She wasn't even watching the game or trying to make any sense out of it anymore, but watching the audience and especially the girls in the front rows told her all she could want to know about how exciting it was, just by seeing how very bad those girls had to go. Because every girl that was still sitting there and still holding even when she clearly had to go that bad was clearly determined to just keep holding it just as long as she had to. At least that shouldn't be too much longer. By her estimation and what she remembered of the schedule Cam showed her earlier there had to be less than a quarter of the game left, as long as it didn't go over the time like she said it could. Clarice really hoped that it wouldn't, and the girls all over the stadium squirming and struggling had to be hoping the same thing. All but the most stubbornly determined girls were squirming openly now, and when Clarice noticed one of them starting to tremble she looked and suddenly found herself watching at the very moment that girl's determination faltered, her composure cracked, then crumbled, and all at once she was squirming just as badly as everyone all around her. She watched the same thing happen to more and more of them, one by one, until there was just a single girl left, right there in the middle of the front row stubbornly sitting very stiff and mostly still. She was a particularly tall girl with particularly striking bright red hair, and she was already trembling and clenching her fists and crossing her legs as tightly as she could. Her lips were pressed together in a tight little line, her face scrunching up in intense concentration and turning almost the same color as her hair. She was doing just about everything she could without joining the squirming all around her. "It's just perfect," Cam murmured. "I was actually a little worried at first, mostly about the juice. But it looks like I got the blend just right after all. If anything it was maybe even a little extra." She chuckled gently, and Clarice nodded absently at that before she thought about it and frowned. "Uh, the blend...?" she started, slightly confused. "I thought, um, isn't it just ordinary juice?" "Oh yeah, it's just juice" Cam nodded. "I mixed it myself. Cherry and raspberry and apple, a little cranberry. And plenty of watermelon." Clarice nodded again, more slowly, but after a moment she remembered something. Watermelon. And apple too, and maybe cranberry although she wasn't so sure about that. Really she'd only glanced through a couple papers about it, but the exact research results weren't really the important part, and now she remembered just what it was about those fruits. "Diuretics..." she breathed, the meaning of what she'd realized becoming clear to her even as she said it. "They're... diuretics." She couldn't quite remember the mechanism of action just now, except that it was maybe better classified at least to some extent as an aquaretic effect, but that wasn't the important part either. Apple juice and especially watermelon juice were both natural diuretics, and when those volunteers took their samples they all drank a nice big dose of that juice along with it, and some of them even got a double dose. Including, she suddenly remembered quite clearly, a certain redheaded girl. She was still looking down at the front row, where that same redhead was now sitting stiffly and trembling and struggling. And between the memory of that girl drinking her juice before and the sight of that girl suffering the consequences now, Clarice's found her mind filling in the details of what happened since then. The redhead girl reaching her seat, the drinks she had with her friends in the parking lot just starting to flow through her kidneys just as she sat down with her friends to enjoy the game. And then while she sat there, the juice she drank along with her sample adding to the flow, and at the same time the diuretic action of that juice gently coaxing her kidneys to increase the flow a little, and then a little more. With all the juice she had to drink, it wouldn't have taken long at all until her kidneys were flowing at full blast and sending all that excess hydration pumping through her ureters and pouring right into her bladder, all while she just sat there and tried to ignore the steadily worsening discomfort. But her kidneys just kept flowing, her bladder just kept filling up, until it was just too full to ignore and all the redhead girl could do was just sit there trembling and struggling and trying as hard as she could just to keep from squirming. But she couldn't. Even as Clarice watched, the redhead girl's trembling turned into a sudden shudder and her expression seemed to shift from determination into dismay, and she shifted position just slightly and just like that she was squirming. The entire front row was squirming, every single girl there quite clearly suffering her own intense distress from her own incredibly full bladder. Their squirming and struggling was just impossible to suppress and totally impossible to hide, so completely obvious that the entire front row might as well have been squealing all together at the top of their lungs 'I gotta go!!!' It was an unbelievable sight, and Clarice just stared, hardly blinking, until suddenly she was snapped out of it by a wave of noise from all around. She jerked in surprise and looked around as the stadium erupted with cheering. Just about everyone was cheering, from the front rows to all the way up here where she was, including Camille right next to her. "They won!" Cam turned to shout at her over the noise, although even Clarice had realized that much. The game was over and the home team had won, so all the fans were cheering for them. "That was so awesome!" She sat back down, still giddy with excitement, and raised her binoculars again. "The whole game was totally awesome. And it looks like they all thought so too." She was looking down at the front row, and Clarice looked down too at the girls there, some laughing and others jumping for joy while a few hugged each other. And all their excitement and victorious exultation was only adding a whole new level to their already urgent distress. Those two girls there laughing were just about doubled over with their hands jammed between their legs, and when that girl there landed from her little jump the little jolt made her eyes go wide and she doubled over too. Another girl that was even more excited and imprudently tried to jump even higher let out a little squeal when she landed and suddenly dropped into a crouch, and those two girls hugging each other were doing so with one arm and had the other hand squeezed between their legs, just like at least half of the other girls around them had at least one hand between their legs too. The cheers were fading now and all over the audience people were getting up to leave, and after a few more moments of celebrating the girls in the front row started lining up and leaving, still squeezing and squirming and struggling as hard as ever. "Come on. We should hurry," Cam took her hand, snapping her out of it as she led the way up the steps. "We can see a little better from up here." There was a sort of balcony area all the way at the top of the stadium, with nobody else there at all just now because it was too small for any seats. As they got up there and raised their binoculars together Clarice realized it really did have an even better view and they could see just about the entire stadium like this. "Good, they're on the way out," observed Cam. The line of girls from the front row was slowly pushing through the crowd and making their way around the curve of the stadium toward the main exit, hardly even glancing at the much longer line at the nearest bathroom as they passed it. The girls themselves were drawing plenty of glances from all around, of course, as those in the crowd and especially in the line turned to look. Another big group of girls trotted up, also squirming and bouncing noticeably as they got into line, only to stop and stare wide-eyed and open-mouthed at the extraordinary sight passing by. Because right now that entire group of highly dedicated college sports fans in tiny colorful miniskirts was acting just like a group of little girls that were trying as hard as they could just to keep from totally wetting their little panties. "Just another minute or two now," Cam was saying. "They just have to make it to the parking lot and we'll have all the samples we could want." Candice nodded anxiously, although she couldn't quite share Cam's show of confidence. She watched the girls approach the stadium's lobby area, with the main entrance that led right out to the parking lot. And she watched their faces, their expressions, all of them just like the expressions of little girls that were right on the brink of totally wetting their little panties. Just looking at their faces like that one by one she could practically hear them all squealing just like little girls, 'I gotta go!', and 'I really gotta go!!', or 'I gotta go so so sooo bad!!!', and then 'I can't believe how bad I gotta go!!!!', and even 'I gotta go *RIGHT NOW*!!!!!'. At last they came around the corner and hurried into the lobby and saw it, and suddenly came to a stop. One by one they stopped right in their tracks, their expressions suddenly shifting as the saw the lobby, with the main entrance and the main bathrooms, and the absolutely enormous line. 'Oh no...' she could see it written right there on all those faces, as all at once the agonized yet eloquent squealing there was replaced by that little whimper of horrified dread. The last of the group came around the corner and the last of the girls saw the huge line there in front of the girls' room, filled with girls squirming and squeezing and struggling to hold it. It snaked back and forth across the lobby and out the other side, disappearing out of sight around the curve of stadium so that it was impossible to even see the end. And for those girls standing there and looking at it, their dread and horror blossoming into despair, that line might as well have been endless. 'Oh no... I- I can't...' those expressions seemed to squeak. A few of them were looking around frantically, hoping to somehow find something that might save them, anything that might give them a way out. But there was nothing to be found, even the boys' room had a line stretching out the door, and the main entrance out to the parking lot were so far away they might as well have been in another time zone. Clarice caught sight of the redhead girl from earlier, with a glint of panic in her eyes and that expression still on her face, the expression of someone perched right on the brink and tipping, sliding, starting to tumble helplessly into total despair. It looked just like the expression of a little girl at just the moment that she finally realized she just couldn't make it, she just didn't have a choice, she just couldn't help it, and she really was just about to totally wet her little panties, because she just couldn't hold it. The despair seemed to sweep over them like a wave, and all those girls gave a little shudder as their expressions shifted entirely into sheer horrified despair that all squealed 'I can't...' But before they could finish that silent cry the redhead girl whipped her head around and cried out aloud, and instead of 'I can't hold it!' what she said was simply "There!", and she started to run for it. The way she was running, on her tiptoes with her thighs still squeezed together and her hands still between them, she still looked very much like a little girl that was very much in danger of wetting her little panties at any moment and was running as fast as she could to make it to the bathroom before it was too late. Except now the redhead girl herself wasn't running for the bathroom at all. "Huh? Wait, what-" Cam had time to cry out in confusion and sudden alarm as she saw where the redhead was running, with a couple of the other girls already running close behind. The parking lot was right there outside the main entrance, where they'd set up all those portable toilets last night, and Cam had simply expected that the girls who had to go the worst would be hurrying there now, to those port-a-potties that were now their only hope of making it in time, as well as the one way for them to safely deliver their samples. But the redhead wasn't running there at all. She never even looked at the entrance, had probably never even noticed the port-a-potties out there and never even realized there was anywhere left that she could go. When she cried out and started running, the 'there' that the redhead was looking at was just a sort of little alley in between the girls' bathroom and the boys' bathroom, just a little bit of space that was left over and didn't even have the concrete floor of the rest of the stadium, just bare dirt and a little gravel. But just now that was just what she needed, and as soon the redhead girl got there she reached under her tiny miniskirt and pulled down her tiny panties and dropped into position, and just like that she just let go. "Aawww!" Cam shouted in frustration as soon as she saw it, and enough of the bystanders standing in line or just passing by made similar surprised exclamations that the two of them could even hear it from up here. With all that noise they definitely couldn't hear the redhead's long moaning sigh, or the softer noise that what she was doing there was making, but they could see what she was doing just fine. And after a moment when she tilted her head back and let her eyes flutter closed they could even see her face and the expression of sheer bliss that blossomed there as the wave of intense relief washed over her. Clarice found herself thinking it was just like the expression that a little girl might make at the moment that she finally let go after she just barely made it, after she just barely managed to hold it just barely long enough to just barely keep from wetting her little panties. And at the same time, Clarice also couldn't help but think that what the redhead girl was doing just now looked nothing at all like any little girl, because there was nothing at all little about the mighty gusher pouring from under her miniskirt. There was just no other word for it. The sheer power of that slender sparkling stream and the long graceful arc that it made as it shot out and passed between her legs and even the way it splashed onto the ground in front of her feet to form a little swirling puddle, it all reminded Clarice of nothing so much as a miniature geyser. And when she thought about it just a bit the analogy suddenly seemed particularly apt, that of a fluid-filled reservoir under internal pressure that grew and grew until it couldn't be contained any longer and at last erupted spectacularly. Because that girl's 'personal reservoir' really was filled to the brim with her 'personal fluid' and it really was under pressure from her detrusor and held inside only by her 'personal squeezing'. And the pressure just grew and grew until it was just unbearable, and the girl decided she just couldn't stand to keep holding it any longer, and as soon as she found just a bit of privacy and got her clothes out of the way she just let go of all that pressure and it just burst out, in a tiny but still spectacular 'personal eruption'. And watching that eruption from high above, Clarice was suddenly struck by what it really meant and her face fell to match Cam's and she whispered, "her sample..." More girls were running up beside the redhead now, joining her there in the alley and reaching under their tiny miniskirts for their tiny panties, pulling them down or just pulling them to the side, and just like that they were all letting go. "Their samples..." Clarice's face fell even more as she watched it, all the girls from the front row crowding in together, all their mighty gushing streams bursting out and flowing freely, all their precious samples spilling out all over the ground. "No way!" Cam cried out in petulant disbelief, "All of them!? And they were so close, too." She pouted, and Clarice sighed. Down there by the bathrooms she watched a few girls from the line hurrying over to hold up a couple of their coats in front of the alley, apparently in the hopes of preserving whatever modesty all the girls squatting there might have left. Then a girl from the line suddenly got out of line and ran over into the alley too, apparently pushed over the edge by the hissing and splashing sounds all those streams were making and left with no other choice but to join them and add her own stream. Another girl did the same, and then another, and Clarice started to think it would maybe be polite to look away. "It was just a little bit farther. Just a little bit longer!" Cam was saying. "Why couldn't they just hold it a litt-" "It's your own fault, you know," she looked away and lowered her binoculars to fix Cam with a skeptical glare, which Cam returned with indignation. Clarice went on, "You should've realized something like this might happen if you just bothered to think it all the way through." Once again, just like Clarice was afraid of, Cam once again hadn't quite thought through all the details of her experimental design. Clarice herself might not have seen it before either, but thinking about it now she could see exactly where everything went wrong. The first part of the plan worked out just perfectly, of course. With all those girls waiting in line they had plenty of volunteers who took their formula and signed their forms, and they all walked into the stadium with the formula in their systems. So when those volunteers took their seats to watch the game the formula was already passing through their kidneys and trickling into their bladders, helped along by Cam's selection of mildly diuretic juices. Then the game itself helped keep it there, keeping the volunteers motivated to stay in their seats and keep watching even as their bladders started to become uncomfortably full. And even when the halftime break gave them all a chance to get up and most of the volunteers took the chance to visit the bathroom, the ones in the front row stayed for their 'unofficial halftime show' and ended up missing their chance and just had to keep holding it. And after that the game just kept getting more and more exciting, so all those sports fans couldn't bear to miss any of it and they had to just keep holding it and holding it, until by the end of the game their bladders were just incredibly full and they could hardly hold it at all. And that was when things started to go wrong. They all had to go so very bad and their bladders all had to be so very very full that their samples were sure to be just extraordinary, just like Cam must have been hoping all along. And they got up and headed straight for the bathroom, just like Cam must have been planning for them to. But when they got to the bathroom and saw the enormous line there, far too long for any of them to ever hope to get through, they didn't keep going to the parking lot and the collection apparatus like Cam must have been expecting. If she just thought it through she might have realized that girls who had to go so very bad after holding it for so very very long weren't going to take the time to try to remember the port-a-potties they might vaguely recall seeing out there hours earlier, and they certainly weren't in any state to go searching for a bathroom either. In that state, as soon as those girls saw that line they must have felt their last flickering hopes of making it to the bathroom suddenly flicker out completely, leaving only undeniable and utterly merciless biological reality. Their poor bladders were just so unbearably full, and being so cruelly squeezed by their involuntary detrusors that they really were in immediate danger of involuntarily emptying themselves, and faced with that absolutely unthinkable possibility, those girls simply did the only thing that they could. They ran into the alley and they pulled down their panties and they all just let go, and just like that the extraordinary samples they had worked so hard to prepare came pouring out and spilled all over the ground. "Face it, Cam," she concluded after thinking it all through. "Your experiment was just poorly designed." Cam glared back, her face growing flushed and her mouth tightening in an even bigger pout as she tried to come up with a response. "It's not over yet!" she managed eventually. "There's still some of them left. They could still make it!" "Maybe so," Claire said with a shrug, raising her binoculars for another look. A sizable crowd was beginning to gather by the alley, some girls murmuring in sympathy while others snickered with derision and most of the guys were just trying to sneak a peek through the improvised curtain. Some other girls just pushed right past while pointedly ignoring both the alley and the crowd, and it looked like they were maybe headed to the parking lot where they would maybe find the apparatus set up there in time for it to maybe collect at least a few samples today. Some of the girls even looked uncomfortable enough that their samples might provide useful results, although certainly nothing like the samples that were forming those swirling puddles and joining into one big puddle while they all soaked into the ground of that alley. "I hope some of the make it at least, but we can't count on them now." If they were going to get a sample that could support their hypothesis, they were going to have to start over. But maybe not quite all the way over. "We'll pick up those samples later, like we planned. But in the meantime we should get another experiment ready." She put the binoculars away and started back down the steps, Cam following along sullenly. "Your general design should be usable with a little work. And I think I've already got some ideas of how to improve it." drxpp, skywalker58, orangelion and 12 others 11 4 Quote Link to comment
omocbc 125 Posted November 20, 2021 Share Posted November 20, 2021 Great story! Quote Link to comment
adriangache 257 Posted November 24, 2021 Share Posted November 24, 2021 Beyond just the omo content this is an extremely well-written story. It manages to include a lot of technical terms without even seeming too technical at all because it's expertly written and conveyed. Can't wait for more! Quote Link to comment
OmoL 103 Posted November 24, 2021 Share Posted November 24, 2021 Really enjoyed this! Quote Link to comment
Markj9494 569 Posted November 27, 2021 Share Posted November 27, 2021 I am not sure how you managed to do it but you got the focus of desperation and all the Omo content in, a lot of scientific information and a compelling story all into this without any one part of those feeling overwhelming. Really well written and I love the premise and idea. Would definitely read more if you ever intended on adding a third part to it. Quote Link to comment
WiiGuy86 641 Posted November 29, 2021 Share Posted November 29, 2021 Wow I remember this story from way back and went back to it a couple times over the years. Great follow up! Quote Link to comment
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